Tamāla Kṛṣṇa: "By the purification of existence, the finer tissues in the memory become sanctified, and, memory being sanctified, one can think of the path of liberation."
Prabhupāda: Just like in our contaminated state we become diseased. What is disease? As soon as you contaminate or infected by some impure thing you become diseased. Similarly, our this disease, material disease, birth, death, old age, they are some kind of disease. Otherwise, I am spirit soul, I am pure, as pure as God because I am part and parcel of God. Due to my impurities of this material body I am suffering. So if you purify your existence then you get the quality in complete pureness of God. You become happy. Ānandamayo 'bhyāsāt (Vedānta-sūtra 1.1.12), sac-cid-ānanda-vigrahaḥ (Bs. 5.1), you become jolly. Brahma-bhūtaḥ prasannātmā (BG 18.54). As soon as you purify yourself and become identified with the existence of God, immediately you become joyful, no anxiety. Brahma-bhūtaḥ prasannātmā (BG 18.54). So you have to purify your existence. If you keep your body impurified, then how you can relish the purified consciousness? So you have to do it. Go on.