Īśa-tantryām, by the laws of material nature, one who is bound up tight, hands and legs... we are all. We cannot, I mean to say, neglect the laws of nature. If you eat little more, then you have to fast for three days. That we actually know. If you expose little to cold, then you have to pay ten dollars to the doctor fine. So they are so much bound up by the laws of nature; still, they are thinking, "I am free. I am independent. Where is God? I am God." Just see. Such foolish persons, that every moment he's being kicked on his face by the boot of material nature, and still he's saying, "I am God, I am independent."
You see? So andhā yathāndhair upanīyamānāḥ (SB 7.5.31). Just like one blind man is speaking other blind men, "Please follow me. I shall lead you to the right path." "But you are blind yourself, and we are also blind. What will be the help?" But no, they will follow.