Rūpa Gosvāmī first met Lord Caitanya at Prayāga (Allahabad, India), and on the Daśāśvamedha bathing ghāṭa of that holy city the Lord instructed him continually for ten days. The Lord particularly instructed Rūpa Gosvāmī on the science of Kṛṣṇa consciousness. These teachings of Lord Caitanya to Śrīla Rūpa Gosvāmī Prabhupāda are narrated in our book Teachings of Lord Caitanya.
Later, Śrīla Rūpa Gosvāmī Prabhupāda elaborated the teachings of the Lord with profound knowledge of revealed scriptures and authoritative references from various Vedic literatures. Śrīla Śrīnivāsa Ācārya describes in his prayers to the six Gosvāmīs that they were all highly learned scholars, not only in Sanskrit but also in foreign languages such as Persian and Arabic. They very scrutinizingly studied all the Vedic scriptures in order to establish the cult of Caitanya Mahāprabhu on the authorized principles of Vedic knowledge.