On the material planets, everyone from Brahmā down to the ant is trying to lord it over material nature, and this is the material disease. As long as this material disease continues, the living entity has to undergo the process of bodily change. Whether he takes the form of a man, demigod or animal, he ultimately has to endure an unmanifested condition during the two devastations—the devastation during the night of Brahmā and the devastation at the end of Brahmā's life. If we want to put an end to this process of repeated birth and death, as well as the concomitant factors of old age and disease, we must try to enter the spiritual planets, where we can live eternally in the association of Lord Kṛṣṇa or His plenary expansions, His Nārāyaṇa forms. Lord Kṛṣṇa or His plenary expansions dominate every one of these innumerable planets, a fact confirmed in the śruti mantras: eko vaśī sarva-gaḥ kṛṣṇa īḍyaḥ/ eko 'pi san bahudhā yo 'vabhāti. (Gopāla-tāpanī Upaniṣad 1.21)
No one can dominate Kṛṣṇa. It is the conditioned soul who tries to dominate material nature and is instead subjected to the laws of material nature and the sufferings of repeated birth and death. The Lord comes here to reestablish the principles of religion, and the basic principle is the development of an attitude of surrender to Him. This is the Lord's last instruction in the Bhagavad-gītā (18.66): sarva-dharmān parityajya mām ekaṁ śaraṇaṁ vraja. "Give up all other processes and just surrender unto Me alone." Unfortunately, foolish men have misinterpreted this prime teaching and misled the masses of people in diverse ways. People have been urged to open hospitals but not to educate themselves to enter into the spiritual kingdom by devotional service. They have been taught to take interest only in temporary relief work, which can never bring real happiness to the living entity. They start varieties of public and semi-governmental institutions to tackle the devastating power of nature, but they don't know how to pacify insurmountable nature. Many men are advertised as great scholars of the Bhagavad-gītā, but they overlook the Gītā's message, by which material nature can be pacified. Powerful nature can be pacified only by the awakening of God consciousness, as clearly pointed out in the Bhagavad-gītā (7.14).
In this mantra, Śrī Īśopaniṣad teaches that one must perfectly know both sambhūti (the Personality of Godhead) and vināśa (the temporary material manifestation), side by side. By knowing the material manifestation alone, one cannot be saved, for in the course of nature there is devastation at every moment (ahany ahani bhūtāni gacchantīha yamā-layam). Nor can one be saved from these devastations by the opening of hospitals. One can be saved only by complete knowledge of the eternal life of bliss and awareness. The whole Vedic scheme is meant to educate men in this art of attaining eternal life. People are often misguided by temporary attractive things based on sense gratification, but service rendered to the sense objects is both misleading and degrading.
We must therefore save ourselves and our fellow man in the right way. There is no question of liking or disliking the truth. It is there. If we want to be saved from repeated birth and death, we must take to the devotional service of the Lord. There can be no compromise, for this is a matter of necessity.