So our natural function is, as described by Śrī Caitanya Mahāprabhu, jīvera 'svarūpa' haya nitya kṛṣṇa dāsa (CC Madhya 20.108-109). This is our constitutional position, that we are eternally servant of Kṛṣṇa, or maidservant of Kṛṣṇa, as you say. But we are trying to become master. So that is sinful. So we are creating so many positions, situations, "How I can become the master." Kṛṣṇa bhuliya jīva bhoga vāñchā kare, pasate māyā tāre jāpaṭiyā dhare (Prema-vivarta). The living entity, forgetting his real position as maidservant of God or servant of God, when he wants to enjoy this material world, that is māyā. Māyā tāre jāpaṭiyā dhare (Prema-vivarta). Immediately. That is sinful.
So this disease is there even in Lord Brahmā down to the small ant. Everyone is trying to enjoy this material . . . The whole material civilization means everyone is trying to enjoy this world, that civilization. So many cars are running here and there, but what is the purpose? The purpose is everyone is trying to enjoy. That is sinful. That is sinful, because you cannot enjoy. Enjoyer is Kṛṣṇa. Bhoktāraṁ yajña-tapasāṁ sarva-loka-maheśvaram (BG 5.29). So long you are trying to encroach upon Kṛṣṇa's jurisdiction—everything is Kṛṣṇa's jurisdiction, but you are falsely trying to enjoy—that is disease.
So this human life specially meant for understanding this truth. That is human life. Kṛṣṇa is educating the human society. Apareyam itas tu viddhi me prakṛtiṁ parāḥ (BG 7.5). First of all He described the material energy, bhūmir āpo 'nalo vāyuḥ (BG 7.4). This is also Kṛṣṇa's energy. Kṛṣṇa is everything—the material, spiritual, marginal, everything.