One day the beautiful-eyed Śrīmatī Rādhārāṇī entered into the forest to collect some flowers to prepare a garland for Kṛṣṇa. While collecting the flowers, She became afraid that someone might see Her, and She felt some fatigue and weakness. This is an instance of guilty feelings caused by labor for Kṛṣṇa.
There is a statement in Rasa-sudhākara that after passing the night with Kṛṣṇa, Rādhārāṇī became so weak that She was unable to get up from bed. When Kṛṣṇa took Her hand to help Her, Rādhārāṇī felt guilty about having passed the night with Him.
Fatigue is felt after walking a long distance, after dancing and after sex activity. In this kind of fatigue there is dizziness, perspiration, inactivity of the limbs, yawning and very heavy breathing.
One day Yaśodā was chasing Kṛṣṇa in the yard after He had offended Her. After a while Yaśodā became very fatigued, and therefore she was perspiring, and her bunched hair became loosened. This is an instance of becoming fatigued because of working too much.
Sometimes all of the cowherd friends of Kṛṣṇa, along with Balarāma, danced together in some ceremony. At these times the garlands on Their necks would move, and They would begin to perspire. Their whole bodies became wet from Their ecstatic dancing. This is an instance of fatigue caused by dancing.
In the Śrīmad-Bhāgavatam, Tenth Canto, 33rd Chapter, 20th verse it is said that after enjoying love affairs with Kṛṣṇa by dancing, embracing and kissing, the gopīs would sometimes become very tired, and Kṛṣṇa, out of His causeless mercy and compassion, would smear their faces with His lotus hands. This is an example of fatigue caused by laboring in the rāsa dance.