From His kingdom the Personality of Godhead sends His bona fide servants to propagate this message by which one can return to Godhead, and sometimes the Lord comes Himself to do this work. Since all living beings are His beloved sons, His parts and parcels, God is more sorry than we ourselves to see the sufferings we are constantly undergoing in this material condition. The miseries of this material world serve to indirectly remind us of our incompatibility with dead matter. Intelligent living entities generally take note of these reminders and engage themselves in the culture of vidyā, or transcendental knowledge. Human life is the best opportunity for the culture of spiritual knowledge, and a human being who does not take advantage of this opportunity is called a narādhama, the lowest of human beings.
The path of avidyā, or advancement of material knowledge for sense gratification, is the path of repeated birth and death. As he exists spiritually, the living entity has no birth or death. Birth and death apply to the outward covering of the spirit soul, the body. Death is compared to the taking off and birth to the putting on of outward garments. Foolish human beings who are grossly absorbed in the culture of avidyā, nescience, do not mind this cruel process. Enamored with the beauty of the illusory energy, they undergo the same miseries repeatedly and do not learn any lessons from the laws of nature.
Therefore the culture of vidyā, or transcendental knowledge, is essential for the human being. Sense enjoyment in the diseased material condition must be restricted as far as possible. Unrestricted sense enjoyment in this bodily condition is the path of ignorance and death. The living entities are not without spiritual senses; every living being in his original, spiritual form has all the senses, which are now materially manifested, being covered by the material body and mind. The activities of the material senses are perverted reflections of the activities of the original, spiritual senses. In his diseased condition, the spirit soul engages in material activities under the material covering. Real sense enjoyment is possible only when the disease of materialism is removed. In our pure spiritual form, free from all material contamination, real enjoyment of the senses is possible. A patient must regain his health before he can truly enjoy sense pleasure again. Thus the aim of human life should not be to enjoy perverted sense enjoyment but to cure the material disease. Aggravation of the material disease is no sign of knowledge, but a sign of avidyā, ignorance. For good health, a person should not increase his fever from 105 degrees to 107 degrees but should reduce his temperature to the normal 98.6. That should be the aim of human life. The modern trend of material civilization is to increase the temperature of the feverish material condition, which has reached the point of 107 degrees in the form of atomic energy. Meanwhile, the foolish politicians are crying that at any moment the world may go to hell. That is the result of the advancement of material knowledge and the neglect of the most important part of life, the culture of spiritual knowledge. Śrī Īśopaniṣad herein warns that we must not follow this dangerous path leading to death. On the contrary, we must develop the culture of spiritual knowledge so that we may become completely free from the cruel hands of death.
This does not mean that all activities for the maintenance of the body should be stopped. There is no question of stopping activities, just as there is no question of wiping out one's temperature altogether when trying to recover from a disease. "To make the best use of a bad bargain" is the appropriate expression. The culture of spiritual knowledge necessitates the help of the body and mind; therefore maintenance of the body and mind is required if we are to reach our goal. The normal temperature should be maintained at 98.6 degrees, and the great sages and saints of India have attempted to do this by a balanced program of spiritual and material knowledge. They never allow the misuse of human intelligence for diseased sense gratification.