Those who cannot understand this truth remain far from the science of devotional service, while those who do understand it are strengthened in their devotional life. Lord Kṛṣṇa is the Supreme Personality of Godhead, the supreme male. So, when the supreme male is present, automatically material nature, his female counterpart, is there to serve Him. Those who falsely pose as the Supreme Person claim to have the material nature at their disposal and conclude that nature is no longer at Lord Kṛṣṇa's beck and call. Naturally this is absurd, and only fools will make such a claim.
Similarly, those philosophical schools which propound that the Supreme Person is subservient to prakṛti, or nature, are also far from the truth. When one thinks about nature and nothing further, the thought is left incomplete.