Being covered by these two bodies, the conditioned soul eternally suffers the pangs of material existence, known as the threefold miseries. He is also subjected to six enemies (lust, anger, etc.). Such is the everlasting disease of the conditioned soul.
Diseased and conditioned, the living entity transmigrates all over the universe. Sometimes he is situated in the upper planetary system, and sometimes he travels in the lower planetary system. In this way he leads his diseased, conditioned life. His disease can be cured only when he meets and follows the expert physician, the bona fide spiritual master.